NGF Receptor / p75NTR / CD271 Antibody from BIORBYT LTD.
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| Antigenic Specificity | NGF Receptor / p75NTR / CD271 |
| Clone | NGFR5 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein G purified |
| Size | 20 ug, 100 ug |
| Concentration | n/a |
| Applications | FACS, IF, IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75. |
| Immunogen | NGFR from A875 melanoma cells was used as the immunogen for the p75NTR antibody. Its epitope has been localized to amino acids 1-160 of the extracellular domain of NGFR/NTR. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P08138 |
| Catalog # | orb749720 |
| Price | $405 |
| Order / More Info | NGF Receptor / p75NTR / CD271 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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