DOG1 / TMEM16A / ANO1 Antibody from BIORBYT LTD.
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| Antigenic Specificity | DOG1 / TMEM16A / ANO1 |
| Clone | DG1/2564R |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | IgG, kappa |
| Format | Protein A purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST's), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GIST's, including all c-kit negative GIST's. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GIST's is nearly identical: 94.4% vs. 94.7%. |
| Immunogen | A portion of amino acids 2-101 from the human protein was used as the immunogen for this recombinant DOG1 antibody. |
| Other Names | n/a |
| Gene, Accession # | Gene ID: 55107, UniProt: Q5XXA6 |
| Catalog # | orb606826 |
| Price | $764 |
| Order / More Info | DOG1 / TMEM16A / ANO1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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