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Antigenic Specificity | Connexin 32 / GJB1 |
Clone | M12.13 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, IF, IHC-Fr, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane a-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another. |
Immunogen | Rat junctional complexes were used as the immunogen for the Connexin 32 antibody. The epitope is known to be located in the cytoplasmic loop (Ref 1). |
Other Names | n/a |
Gene, Accession # | UniProt: P08034 |
Catalog # | orb386047 |
Price | $764 |
Order / More Info | Connexin 32 / GJB1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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