Connexin 32 / GJB1 Antibody from BIORBYT LTD.

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Antigenic SpecificityConnexin 32 / GJB1
CloneM12.13
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsFACS, IF, IHC-Fr, WB
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DescriptionThis Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane a-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another.
ImmunogenRat junctional complexes were used as the immunogen for the Connexin 32 antibody. The epitope is known to be located in the cytoplasmic loop (Ref 1).
Other Namesn/a
Gene, Accession #UniProt: P08034
Catalog #orb386047
Price$764
Order / More InfoConnexin 32 / GJB1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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