Langerin / CD207 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Langerin / CD207 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Langerin / CD207 |
| Clone | LGRN/7357 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG |
| Format | unconjugated |
| Size | 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein. |
| Immunogen | A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the Langerin antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q9UJ71 |
| Catalog # | orb1823958 |
| Price | $405 |
| Order / More Info | Langerin / CD207 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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Email: info@biorbyt.com
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