Phospho-COT (Thr290) Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Phospho-COT (Thr290) antibody, protein, ELISA kits.
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| Antigenic Specificity | Phospho-COT (Thr290) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | n/a |
| Applications | ELISA, ICC, IHC, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | mitogen-activated protein kinase kinase kinase 8(MAP3K8) Homo sapiens This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human COT around the phosphorylation site of Thr290. AA range:256-305 |
| Other Names | Mitogen-activated protein kinase kinase kinase 8; Cancer Osaka thyroid oncogene; Proto-oncogene c-Cot; Serine/threonine-protein kinase cot; Tumor progression locus 2 |
| Gene, Accession # | Gene ID: 1326, UniProt: P41279 |
| Catalog # | orb1730627 |
| Price | $296 |
| Order / More Info | Phospho-COT (Thr290) Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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