CD19 / B-lymphocyte marker Antibody from BIORBYT LTD.

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Antigenic SpecificityCD19 / B-lymphocyte marker
CloneCD19/3116
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsELISA, FACS, IHC-P
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DescriptionCD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms.
ImmunogenA recombinant human partial protein (amino acids 96-281) was used as the immunogen for the CD19 antibody.
Other Namesn/a
Gene, Accession #UniProt: P15391
Catalog #orb640038
Price$764
Order / More InfoCD19 / B-lymphocyte marker Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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