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Antigenic Specificity | NSE / Neuron Specific Enolase |
Clone | ENO2/1462 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2b, kappa |
Format | Protein G purified |
Size | 20 ug, 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This mAb recognizes a protein of about 50 kDa which is identified as gamma-Enolase/Neuron Specific Enolase/Enolase 2. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue and gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament. |
Immunogen | Amino acids 416-433 of human NSE were used as the immunogen for this Neuron Specific Enolase antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P09104 |
Catalog # | orb750096 |
Price | $405 |
Order / More Info | NSE / Neuron Specific Enolase Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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