NSE / Neuron Specific Enolase Antibody from BIORBYT LTD.

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Antigenic SpecificityNSE / Neuron Specific Enolase
CloneENO2/1462
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2b, kappa
FormatProtein G purified
Size20 ug, 100 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionThis mAb recognizes a protein of about 50 kDa which is identified as gamma-Enolase/Neuron Specific Enolase/Enolase 2. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue and gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament.
ImmunogenAmino acids 416-433 of human NSE were used as the immunogen for this Neuron Specific Enolase antibody.
Other Namesn/a
Gene, Accession #UniProt: P09104
Catalog #orb750096
Price$405
Order / More InfoNSE / Neuron Specific Enolase Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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