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Antigenic Specificity | von Willebrand Factor / vWF |
Clone | VWF/4458 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. |
Immunogen | Recombinant full-length human VWF protein was used as the immunogen for the von Willebrand Factor antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P04275 |
Catalog # | orb1825805 |
Price | $764 |
Order / More Info | von Willebrand Factor / vWF Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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