Occludin Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Occludin antibody, protein, ELISA kits.
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| Antigenic Specificity | Occludin |
| Clone | OCLN/2182 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 100 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of Occludin. Expression of Occludin is upregulated by polyunsaturated fatty acids, increasing trans-endothelial cell resistance and reducing cellular permeability to large molecules. The level of Occludin varies greatly depending on tissue; in brain tissue, Occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial Occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction. |
| Immunogen | A recombinant human protein fragment (within amino acids 282-415) was used as the immunogen for the Occludin antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q16625 |
| Catalog # | orb1823351 |
| Price | $764 |
| Order / More Info | Occludin Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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