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Antigenic Specificity | GFAP R416WT |
Clone | S206B-9 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 100 ug |
Concentration | 1 mg/ml |
Applications | ICC, IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal to GFAP R416WT (Biotin). The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia.. |
Immunogen | Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse. > 50% identity with other proteins (Vimentin, Desmin and Peripherin). |
Other Names | Glial fibrillary acidic protein, Intermediate filament protein, Astrocyte, gfapl, DKFZp459C0729, MGC139638, FLJ45472, AI836096, GFAP |
Gene, Accession # | Gene ID: 2670, UniProt: P14136 |
Catalog # | orb150543 |
Price | $567 |
Order / More Info | GFAP R416WT Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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