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Antigenic Specificity | WT1 / Wilms Tumor 1 |
Clone | WT1/1434R |
Host Species | Recombinant Rabbit |
Reactive Species | human, rat |
Isotype | IgG, kappa |
Format | Protein A purified |
Size | 20 ug, 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas. |
Immunogen | A recombinant protein was used as the immunogen for the recombinant WT1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P19544 |
Catalog # | orb750181 |
Price | $405 |
Order / More Info | WT1 / Wilms Tumor 1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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