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Antigenic Specificity | MLL5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to MLL5.MLL5 is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family. It is a histonemethyltransferase that specifically mono-and dimethylates Lys-4 of histone H3 (H3K4me1 andH3K4me2). Lys-4 methylation of H3 represents a specific tag for epigenetic transcriptional activation.It is a key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulationof hematopoietic stem cell self-renewal by a mechanism that involves DNA methylation.Overexpression of MLL5 inhibits cell cycle progression while knockdown induces cell cycle arrest atboth the G1 and G2/M phases. |
Immunogen | N-terminal region of human MLL5 |
Other Names | MLL5,FLJ10078,FLJ14026,HDCMC04P,KMT2E,MGC70452 |
Gene, Accession # | n/a |
Catalog # | orb66810 |
Price | $527 |
Order / More Info | MLL5 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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