Desmin Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Desmin antibody, protein, ELISA kits.
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| Antigenic Specificity | Desmin |
| Clone | D33 |
| Host Species | Mouse |
| Reactive Species | human, rat |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain α-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. |
| Immunogen | Human leiomyoma proteins were used as the immunogen for the Desmin antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P17661 |
| Catalog # | orb1716302 |
| Price | $405 |
| Order / More Info | Desmin Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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