CD154 Antibody from BIORBYT LTD.
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| Antigenic Specificity | CD154 |
| Clone | 24-31 |
| Host Species | n/a |
| Reactive Species | human, primate |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests |
| Concentration | n/a |
| Applications | FC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family, and is expressed primarily on activated CD4+ lymphocytes, but also on mast cells, basophils, eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells, including dendritic cells, macrophages, and B cells, and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center. |
| Immunogen | human CD154 fusion protein |
| Other Names | CD40L, CD40 ligand, TNFSF5, Ly62, gp39, T-BAM |
| Gene, Accession # | Gene ID: 21947, UniProt: P27548 |
| Catalog # | orb1806414 |
| Price | $439 |
| Order / More Info | CD154 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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P: +44 (0)1223 859 353
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info@biorbyt.com
http://www.biorbyt.com
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Email: info@biorbyt.com
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