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Antigenic Specificity | MOCOS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to MOCOS.Molybdenum cofactor sulfurase (MOCOS) belongs to the class-V pyridoxal-phosphate-dependentaminotransferase family. It sulfurates the molybdenum cofactor. Sulfation of molybdenum is essentialfor xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenumcofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain isable to reduce N-hydroxylated prodrugs, such as benzamidoxime. Defects in MOCOS are the causeof xanthinuria type 2 (XU2). Patients suffering XU2 cannot metabolize allopurinol into oxypurinol dueto dual deficiency of xanthine dehydrogenase and aldehyde oxidase. |
Immunogen | N-terminal region of human MOCOS |
Other Names | MOCOS,Molybdenum cofactor sulfurase,MCS,MOS,MoCo sulfurase,hMCS |
Gene, Accession # | UniProt: Q96EN8 |
Catalog # | orb67220 |
Price | $527 |
Order / More Info | MOCOS Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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