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Antigenic Specificity | Phospho-Src (Tyr419) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | FC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2). |
Immunogen | A synthesized peptide derived from human Phospho-Src (Y419) |
Other Names | SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src |
Gene, Accession # | Gene ID: 6714, UniProt: P12931 |
Catalog # | orb1730689 |
Price | $296 |
Order / More Info | Phospho-Src (Tyr419) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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