Estrogen Receptor beta Antibody from BIORBYT LTD.

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Antigenic SpecificityEstrogen Receptor beta
CloneESR2/3207
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsELISA
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DescriptionEstrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.
ImmunogenRecombinant full-length human protein was used as the immunogen for the Estrogen Receptor beta antibody.
Other Namesn/a
Gene, Accession #UniProt: Q92731
Catalog #orb639643
Price$764
Order / More InfoEstrogen Receptor beta Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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