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Antigenic Specificity | TLR2 |
Clone | TLR2/3894R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | Protein A purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. |
Immunogen | Recombinant full-length human TLR2 protein was used as the immunogen for the recombinant TLR2 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: O60603 |
Catalog # | orb699515 |
Price | $764 |
Order / More Info | TLR2 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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