Semaphorin-4D / SEMA4D Antibody from BIORBYT LTD.
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|---|---|
| Antigenic Specificity | Semaphorin-4D / SEMA4D |
| Clone | 133-1C6 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM, kappa |
| Format | PEG purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | FACS, IF |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation. |
| Immunogen | PHA stimulated human peripheral blood lymphocytes were used as the immunogen for the Semaphorin-4D antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q92854 |
| Catalog # | orb749458 |
| Price | $764 |
| Order / More Info | Semaphorin-4D / SEMA4D Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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