ENO1 Antibody from BIORBYT LTD.
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| Antigenic Specificity | ENO1 |
| Clone | 4H7 |
| Host Species | Mouse |
| Reactive Species | human, monkey, mouse, rat |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | 1mg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.MiscellaneousUsed as a diagnostic marker for many tumors and, in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest. Also marker for endometriosis. Antibodies against alpha-enolase are present in sera from patients with cancer-associated retinopathy syndrome (CAR), a progressive blinding disease which occurs in the presence of systemic tumor growth, primarily small-cell carcinoma of the lung and other malignancies. Is identified as an autoantigen in Hashimoto encephalopathy (HE) a rare autoimmune disease associated with Hashimoto thyroiditis (HT). HT is a disorder in which destructive processes overcome the potential capacity of thyroid replacement leading to hypothyroidism. |
| Immunogen | Purified recombinant human Enolase-1 protein fragments expressed in E.coli. |
| Other Names | NNE; PPH; MPB1; ENO1L1; HEL-S-17 |
| Gene, Accession # | Gene ID: 2023, UniProt: P06733 |
| Catalog # | orb1732713 |
| Price | $345 |
| Order / More Info | ENO1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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