Transferrin Receptor / TFRC / CD71 Antibody from BIORBYT LTD.

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Antigenic SpecificityTransferrin Receptor / TFRC / CD71
CloneTFRC/1817
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsELISA, IHC-P
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DescriptionIt recognizes a ~85-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
ImmunogenAmino acids 94-212 (extracellular domain) of the human protein were used as the immunogen for the Transferrin Receptor / CD71 antibody.
Other Namesn/a
Gene, Accession #UniProt: P02786
Catalog #orb386209
Price$764
Order / More InfoTransferrin Receptor / TFRC / CD71 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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