GBL Antibody from BIORBYT LTD.

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Antigenic SpecificityGBL
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatProtein A purified
Size100 ug, 25 ug
Concentrationn/a
ApplicationsWB
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DescriptionGBL (G protein beta subunit-like), also called MLST8 (MTOR associated protein, LST8 homolog), is a subunit of the mTOR signaling complexes mTORC1 and mTORC2, which help regulate cell growth and survival in response to growth factor (mTORC1 & 2) and nutrient (mTORC1) signaling. It is required for the phosphorylation of S6 kinase and the signal adaptor protein Insulin receptor substrate 1 and S473 phosphorylation of AKT. GBL is also a regulator of TNFa-induced NF-kB activity, with overexpression inhibiting and down-regulation enhancing NF-kB signaling (Kim et al, 2008).
ImmunogenA recombinant protein fragment from the internal region of human GBL was used as the immunogen for this antibody.
Other Namesn/a
Gene, Accession #Gene ID: 64223
Catalog #orb248173
Price$643
Order / More InfoGBL Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

http://www.biorbyt.com

U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558


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