FBXW7 Antibody from BIORBYT LTD.

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Antigenic SpecificityFBXW7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size100 ul
Concentration100 µg/ml BSA
ApplicationsWB
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DescriptionRabbit polyclonal to FBXW7. F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds to phosphorylated target proteins. Furthermore, FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
ImmunogenC-terminal region of human FBXW7
Other NamesF-box/WD repeat-containing protein 7, Archipelago homolog, hAgo, F-box and WD-40 domaincontaining protein 7, F-box protein FBX30, SEL-10, hCdc4, FBW7, FBX30, SEL10
Gene, Accession #UniProt: Q969H0
Catalog #orb131883
Price$527
Order / More InfoFBXW7 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

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