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Antigenic Specificity | FBXW7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | 100 µg/ml BSA |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to FBXW7. F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds to phosphorylated target proteins. Furthermore, FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. |
Immunogen | C-terminal region of human FBXW7 |
Other Names | F-box/WD repeat-containing protein 7, Archipelago homolog, hAgo, F-box and WD-40 domaincontaining protein 7, F-box protein FBX30, SEL-10, hCdc4, FBW7, FBX30, SEL10 |
Gene, Accession # | UniProt: Q969H0 |
Catalog # | orb131883 |
Price | $527 |
Order / More Info | FBXW7 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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