TSC2 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-TSC2 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | TSC2 |
| Clone | RB42286 |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 400 ul, 80 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to TSC2. In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. Stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro. Mutations in TSC2 lead to constitutive activation of RAP1A in tumors. |
| Immunogen | Synthetic Peptide |
| Other Names | TSC2, TSC4, Tuberin, Tuberin, Tuberous sclerosis 2 protein |
| Gene, Accession # | UniProt: P49815 |
| Catalog # | orb106932 |
| Price | $561 |
| Order / More Info | TSC2 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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