C/EBP epsilon / CEBPE Antibody from BIORBYT LTD.
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| Antigenic Specificity | C/EBP epsilon / CEBPE |
| Clone | PCRP-CEBPE-1G12 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 20 ug |
| Concentration | n/a |
| Applications | FACS, IF |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The transcription factor C/EBP Alpha (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP Alpha regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP Alpha uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic Alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP Alpha appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP beta, C/EBP gamma, C/EBP delta and C/EBP epsilon, all of which exhibit similar DNA-binding specificities and affinities to C/EBP Alpha. Furthermore, C/EBP beta and C/EBP delta readily form heterodimers both with each other as well as with C/EBP Alpha. |
| Immunogen | Recombinant human protein was used as the immunogen for the C/EBP epsilon antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q15744 |
| Catalog # | orb1825575 |
| Price | $405 |
| Order / More Info | C/EBP epsilon / CEBPE Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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