CUL3 Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | CUL3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to CUL3.CUL3 is a component of a ubiquitin E3 ligase that is essential for mitotic division. CUL3 is a corecomponent of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligasecomplexes which mediate the ubiquitination and subsequent proteasomal degradation of targetproteins. As a scaffold protein, CUL3 may contribute to catalysis through positioning of the substrateand the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex isdependent on the neddylation of the cullin subunit and is inhibited by the association of thedeneddylated cullin subunit with TIP120A/CAND1 (By similarity). BCR(SPOP) is involved inubiquitination of BMI1/PCGF4, H2AFY and DAXX, and probably GLI2 or GLI3, as well as cyclin E andof cyclin D1. |
| Immunogen | C-terminal region of human CUL3 |
| Other Names | CUL3,Cullin3,KIAA0617 |
| Gene, Accession # | UniProt: Q13618 |
| Catalog # | orb66953 |
| Price | $527 |
| Order / More Info | CUL3 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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