Histone H1 Antibody from BIORBYT LTD.
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| Antigenic Specificity | Histone H1 |
| Clone | SPM256 |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2a, kappa |
| Format | Protein G purified |
| Size | 20 ug, 100 ug |
| Concentration | n/a |
| Applications | FACS, IF, IHC-P, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation. |
| Immunogen | Nuclei of human leukemia biopsy cells were used as the immunogen for the anti-Histone H1 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P07305 |
| Catalog # | orb749551 |
| Price | $405 |
| Order / More Info | Histone H1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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