CELA3B / Elastase 3B Antibody from BIORBYT LTD.

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Antigenic SpecificityCELA3B / Elastase 3B
CloneELTS3B-4R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG, kappa
FormatProtein A purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionElastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [RefSeq]
ImmunogenAmino acids 82-238 from the human protein were used as the immunogen for the recombinant CELA3B antibody.
Other Namesn/a
Gene, Accession #UniProt: P08861
Catalog #orb534457
Price$764
Order / More InfoCELA3B / Elastase 3B Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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