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Antigenic Specificity | Semaphorin 4D |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | ICC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA. |
Immunogen | A synthetic peptide of human Semaphorin 4D |
Other Names | CD100; COLL4; SEMAJ; coll-4; C9orf164; M-sema-G |
Gene, Accession # | Gene ID: 10507, UniProt: Q92854 |
Catalog # | orb1731375 |
Price | $345 |
Order / More Info | Semaphorin 4D Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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