Edit |   |
---|---|
Antigenic Specificity | NKIRAS1 |
Clone | NRAS285 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 100 ug, 25 ug |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity. |
Immunogen | A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody. |
Other Names | n/a |
Gene, Accession # | Gene ID: 28512, UniProt: Q9NYS0 |
Catalog # | orb248144 |
Price | $643 |
Order / More Info | NKIRAS1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558