SOX11 Antibody from BIORBYT LTD.

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Antigenic SpecificitySOX11
CloneSOX11/3235R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG, kappa
FormatProtein A purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionRecognizes a protein of ~47kDa, identified as SOX11. This MAb is highly specific and does not cross-react with other members of the SOX-family. Mantle cell lymphoma (MCL) accounts for 5% to 10% of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of Cyclin D1. Cyclin D1 overexpression is the hallmark of MCL. However, approximately 5%-10% of MCLs lack Cyclin D1 expression and may be misdiagnosed. Almost all Cyclin D1-positive as well as Cyclin D1-negative MCL, show overexpression of SOX-11. The detection of this transcription factor is a useful biomarker for identifying true cyclin D1-negative MCL.
ImmunogenA portion of amino acids 300-400 from the human protein was used as the immunogen for the recombinant SOX11 antibody.
Other Namesn/a
Gene, Accession #UniProt: P35716
Catalog #orb699754
Price$764
Order / More InfoSOX11 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

http://www.biorbyt.com

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Email: info@biorbyt.com
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