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Antigenic Specificity | MZF1 / Myeloid zinc finger 1 |
Clone | PCRP-MZF1-1E8 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | FACS, IF, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Zinc finger genes that encode metal-binding proteins are transcriptional regulators of other genes. Myeloid zinc finger 1 (MZF-1), also designated zinc finger protein 42, and transcription factor ZBP-89, also designated zinc finger protein 148, belong to the Kruppel C2H2-type zinc-finger protein family. The gene encoding for the MZF-1 protein maps to chromosome 19q13.43 while the gene encoding for ZBP-89 is localized on chromosome 3q21. These proteins are nuclear proteins involved in the regulation of transcriptional events. MZF-1 regulates transcription during hemopoietic development and plays a role in myeloid cell differentiation. MZF-1 regulates the CD34 promoter in a tissue-specific manner. MZF-1 and FHL3 can form a complex of high molecular mass with other proteins in the nucleus. It is induced by retinoic acid and is primarily expressed in differentiating myeloid cells. |
Immunogen | A recombinant partial protein sequence (within amino acids 37-128) from the human protein was used as the immunogen for the Myeloid zinc finger 1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P28698 |
Catalog # | orb1824627 |
Price | $405 |
Order / More Info | MZF1 / Myeloid zinc finger 1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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