CYP2E1 Antibody from BIORBYT LTD.
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| Antigenic Specificity | CYP2E1 |
| Clone | M12P4H2 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein G purified |
| Size | 20 ug, 100 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases, which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines, which are pre-mutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. |
| Immunogen | The C-terminal amino acid sequence HIGFGCIPPR was used as the immunogen for the CYP2E1 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P05181 |
| Catalog # | orb606522 |
| Price | $405 |
| Order / More Info | CYP2E1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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