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Antigenic Specificity | Integrin beta 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling. |
Immunogen | Recombinant protein of mouse Integrin beta 4 |
Other Names | CD104 |
Gene, Accession # | Gene ID: 192897, UniProt: A2A863 |
Catalog # | orb1730199 |
Price | $296 |
Order / More Info | Integrin beta 4 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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