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Antigenic Specificity | Hu TCR Vdelta2 |
Clone | B6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | phycoerythrin (PE) conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | FC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR Vdelta2 is a variant of TCR delta chain, that is present on a major subset of human gamma/delta T cells. TCR Vgamma9/Vdelta2 (or Vgamma2/Vdelta2) T cells are able to recognize and kill various tumor cells, as this receptor heterodimer binds to certain phosphoantigens, expressed by tumors. They can recognize these antigens in an MHC-unrestricted manner. Similarly to NK cells, Vdelta2 T cells express MHC I receptors and killer Ig-like receptors, that are involved in tumor recognition and cytolysis. The potently cytotoxic subset of them is identified by cell surface expression of polysialyated CD56. |
Immunogen | human recombinant TCR Vdelta2 |
Other Names | TCRVD2 |
Gene, Accession # | n/a |
Catalog # | orb1176619 |
Price | $439 |
Order / More Info | Hu TCR Vdelta2 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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