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Antigenic Specificity | CD45RO (T-cell marker) |
Clone | CDLA45RO-1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45RO is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. CD45RO contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. It also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. [RefSeq] |
Immunogen | Recombinant human protein was used as immunogen for this CD45RO antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P08575 |
Catalog # | orb385805 |
Price | $764 |
Order / More Info | CD45RO (T-cell marker) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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