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Antigenic Specificity | CD27 |
Clone | 203.6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG3, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis. |
Immunogen | Sezary cells were used as the immunogen for the CD27 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P26842 |
Catalog # | orb749881 |
Price | $764 |
Order / More Info | CD27 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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