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Antigenic Specificity | Cytokeratin 5 / KRT5 |
Clone | KRT5/8814R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG, kappa |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This mAb recognizes a protein of 58kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, yoepithelial, and mesothelium. Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express. Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5. |
Immunogen | A recombinant partial protein sequence (within amino acids 316-590) from the human protein was used as the immunogen for the Cytokeratin 5 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P13647 |
Catalog # | orb1825722 |
Price | $405 |
Order / More Info | Cytokeratin 5 / KRT5 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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