XPO4 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-XPO4 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | XPO4 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | IgG |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | 1mg/ml |
| Applications | IP, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO4 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. |
| Immunogen | A synthetic peptide of human Exportin 4 |
| Other Names | exp4 |
| Gene, Accession # | Gene ID: 64328, UniProt: Q9C0E2 |
| Catalog # | orb1731995 |
| Price | $345 |
| Order / More Info | XPO4 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240
info@biorbyt.com
http://www.biorbyt.com
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558
Profile of BIORBYT LTD.
Return to Antibodies