Phosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) Antibody from BIORBYT LTD.

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Antigenic SpecificityPhosoho-ErbB 2/EGFR (Tyr1248/Tyr1173)
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsIP, WB
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DescriptionThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.
ImmunogenA synthetic phosphopeptide corresponding to residues surrounding Tyr1248 of human ErbB 2
Other NamesERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD antigen CD340
Gene, Accession #Gene ID: 2064, UniProt: P04626
Catalog #orb1733133
Price$345
Order / More InfoPhosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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