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Antigenic Specificity | Phosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Tyr1248 of human ErbB 2 |
Other Names | ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD antigen CD340 |
Gene, Accession # | Gene ID: 2064, UniProt: P04626 |
Catalog # | orb1733133 |
Price | $345 |
Order / More Info | Phosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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