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Antigenic Specificity | CD2 |
Clone | UMCD2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, Functional Studies, IF, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific Tcell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells. |
Immunogen | Human Thymocytes/Sezary T cells were used as the immunogen for this CD2 antibody. |
Other Names | n/a |
Gene, Accession # | Gene ID: 914 |
Catalog # | orb749309 |
Price | $764 |
Order / More Info | CD2 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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