ARS2 Antibody from BIOSS ANTIBODIES

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Antigenic SpecificityARS2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatProtein A purified
Size100ul
Concentration1ug/ul
ApplicationsWB (1:100-1000), IHC-P (1:100-500), IF (IHC-P) (1:50-200)
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DescriptionARS2 Polyclonal Antibody. ARS2(Arsenite resistance protein 2) confers arsenite resistance. The protein belongs to the ARS2 family. Arsenic is a human carcinogen whose mechanism of action is unknown. The arsenite acts as a comutagen by interfering with DNA repair. Two genes, ASR1(Arsenite resistance protein 1) and ASR2 (Arsenite resistance protein 2), confer arsenite resistance to arsenite-sensitive cells. ASR1 shows almost complete homology with the rat fau gene, a tumor suppressor gene which contains a ubiquitin like region fused to S30 ribosomal protein. Arsenite inhibits ubiquitin dependent proteolysis. The tumor suppressor fau gene product or some other aspect of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the genotoxicity and carcinogenicity of arsenite.
ImmunogenKLH conjugated synthetic peptide derived from human ARS2
Other NamesARS2 protein; Arsenate resistance protein ARS2; Arsenite resistance protein 2; Arsenite resistance protein; ASR2; MGC126427; Serrate; Serrate RNA effector molecule homolog Arabidopsis; Serrate RNA effector molecule homolog; SRRT; SRRT_HUMAN.
Gene, Accession #Entrez Gene ID: 51593
Catalog #bs-7970R
Priceplease inquire
Order / More InfoARS2 Antibody from BIOSS ANTIBODIES
Product Specific Referencesn/a
BIOSS ANTIBODIES
BIOSS ANTIBODIES
BIOSS ANTIBODIES
500 West Cummings Park, Suite 6500
Woburn MA 01801
P: 1-800-501-7654

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