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Antigenic Specificity | APC |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | IgG |
Format | affinity purified |
Size | 100 µl |
Concentration | n/a |
Applications | IP, IF, IHC, ICC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Boster Bio Anti-APC Monoclonal Antibody catalog # M00008. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. |
Immunogen | A synthesized peptide derived from human APC Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF) -induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. |
Other Names | n/a |
Gene, Accession # | APC, UniProt: P25054 |
Catalog # | M00008 |
Price | $370 |
Order / More Info | APC Antibody from BOSTER BIO |
Product Specific References | n/a |