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Antigenic Specificity | CEA + GD2 Tandem Fab-DT (bispecific immunotoxin) |
Clone | monoclonal |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | n/a |
Format | bispecific immunotoxin |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Anti-CEA x Anti-GD2 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin). Recombinant Anti-CEA x Anti-GD2 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the diphtheria toxin (DT) fused to a tandem Fab recognizing CEA and GD2. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver DT to antigen-specific cells. Then DT can inhibit protein synthesis and kill the target cells. The bispecific immunotoxin is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy. |
Immunogen | n/a |
Other Names | CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100 |
Gene, Accession # | UniProt: A0A024R0K5 |
Catalog # | BSFAB-DT005 |
Price | please inquire |
Order / More Info | CEA + GD2 Tandem Fab-DT (bispecific immunotoxin) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |