Edit |   |
---|---|
Antigenic Specificity | HER3 + IGF1R Tandem Fab-MEL (bispecific immunotoxin) |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | bispecific immunotoxin |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Human Anti-HER3 x Human Anti-IGF1R Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin). Recombinant Anti-HER3 x Anti-IGF1R Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the Melittin (MEL) fused to a tandem Fab recognizing HER3 and IGF1R. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver MEL to antigen-specific cells. Then MEL is a cytolytic peptide and can kill the target cells. The bispecific immunotoxin is designed for the research of Pancreatic cancer; Hepatocellular carcinoma (HCC) therapy. |
Immunogen | n/a |
Other Names | ERBB3; erb-b2 receptor tyrosine kinase 3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; receptor tyrosine-protein kinase erbB-3; proto-oncogene-like protein c-ErbB-3; human epidermal growth factor receptor 3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 |
Gene, Accession # | UniProt: P21860 |
Catalog # | BSFAB-MEL034 |
Price | please inquire |
Order / More Info | HER3 + IGF1R Tandem Fab-MEL (bispecific immunotoxin) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |