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Antigenic Specificity | CD186 |
Clone | CBP3962 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | FC; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat Anti-Mouse CD186 Monoclonal Antibody (CBP3962) |
Immunogen | mCXCR6-transfectants |
Other Names | C-X-C chemokine receptor type 6 is a protein that in humans is encoded by the CXCR6 gene.[5][6][7] CXCR6 has also recently been designated CD186 (cluster of differentiation 186). CXCR6 has been identified as an entry coreceptor used by HIV-1 and SIV to enter target cells; in conjunction with CD4.[5][6][7][8] It is a minor coreceptor for HIV-1; nearly all strains of which use CCR5 and/or CXCR4. Most SIV strains can use CXCR6 and recent evidence suggests that in monkeys that serve as the natural hosts of SIV; CXCR6 may be a major coreceptor.[8] CXCR6 was previously known as "Bonzo" and "STRL33" in the HIV/SIV field. |
Gene, Accession # | UniProt: UniProt: Q9EQ16 |
Catalog # | NAB2012893LS |
Price | please inquire |
Order / More Info | CD186 Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |