DNMT1 + SHH (bispecific) Antibody from CREATIVE BIOLABS, INC.
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| Antigenic Specificity | DNMT1 + SHH (bispecific) |
| Clone | monoclonal |
| Host Species | Recombinant Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | bispecific |
| Size | n/a |
| Concentration | n/a |
| Applications | FuncS; Promising therapeutic agent; |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recombinant Anti-DNMT1 x Anti-SHH Bispecific Antibody (Fab-IgG). Recombinant Anti-DNMT1 x Anti-SHH Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can bind two factors simultaneously, block Hedgehog binding to PTCH, downregulate of DNMT1 and block DNA methylation. It is designed for the research of Hormone refractory breast cancer (HRBC) therapy. |
| Immunogen | n/a |
| Other Names | AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN; DNA methyltransferase 1; DNMT1 |
| Gene, Accession # | UniProt: I6L9H2 |
| Catalog # | FABIG-150 |
| Price | please inquire |
| Order / More Info | DNMT1 + SHH (bispecific) Antibody from CREATIVE BIOLABS, INC. |
| Product Specific References | n/a |
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356
info@creative-biolabs.com
http://www.creative-biolabs.com
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