Edit |   |
---|---|
Antigenic Specificity | CD19 + CD22 Tandem Fab-PE (bispecific immunotoxin) |
Clone | monoclonal |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | n/a |
Format | bispecific immunotoxin |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin). Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the Pseudomonas exotoxin (PE) fused to a tandem Fab recognizing CD19 and CD22. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver PE to antigen-specific cells. Then PE can inhibit protein synthesis and kill the target cells. The bispecific immunotoxin is designed for the research of B cell lymphoma; Leukemia therapy. |
Immunogen | n/a |
Other Names | CD19; CD19 molecule; Cluster of differentiation 19; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4 |
Gene, Accession # | UniProt: P15391 |
Catalog # | BSFAB-PE003 |
Price | please inquire |
Order / More Info | CD19 + CD22 Tandem Fab-PE (bispecific immunotoxin) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |