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Antigenic Specificity | CD2 + EGFR (bispecific) |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | bispecific |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Human Anti-CD2 x Human Anti-EGFR Bispecific Antibody (Minibody). Recombinant Anti-CD2 x Anti-EGFR Bispecific Antibody (Minibody) is designed to be expressed as the anti-CD2 scFv fused to N-terminus of Knob-CH3 domain and the anti-EGFR scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can retarget T cells to tumor cells. It is designed for the research of Head and neck cancer; Colorectal cancer (CRC); Glioblastoma multiforme (GBM); Squamous cancer; Glioblastoma; Medulloblastoma; Non-small cell lung cancer (NSCLC); Renal cell cancer (RCC); Solid tumors therapy. |
Immunogen | n/a |
Other Names | CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; leukocyte function-associated antigen-2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor |
Gene, Accession # | UniProt: P06729 |
Catalog # | MiniB-H223 |
Price | please inquire |
Order / More Info | CD2 + EGFR (bispecific) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |