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Antigenic Specificity | SARS S |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | SARS |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | Neut, |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Human Anti-SARS S Antibody (80R). Recombinant Human Antibody (80R) is capable of binding to SARS S, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-SARS S mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti-SARS S proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. We show that the 80R-binding epitope on the S1 RBD overlaps very closely with the ACE2 binding site, providing a rationale for the strong binding and broad neutralizing ability of the antibody. |
Immunogen | SARS Spike glycoprotein |
Other Names | Spike glycoprotein; S protein |
Gene, Accession # | UniProt: P59594 |
Catalog # | PABZ-139 |
Price | please inquire |
Order / More Info | SARS S Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |